Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p094 | (1) | WCRB2014

The antioxidative effect of carboxyethylgermaniumsesquioxide (Ge-132) on in vitro maturation of porcine oocytes and subsequent embryonic development after in vitro fertilization and parthenogenetic activation

Kim Eunhye , Hyun Sang-Hwan

The carboxyethylgermaniumsesquioxide (Ge-132) is an organogermanium compound known to have anti-oxidative effect. In this study, we examined the effect of Ge-132 on in vitro maturation (IVM) of porcine oocytes analyzing intracellular glutathione (GSH) and reactive oxygen species (ROS) levels, mRNA expression levels and subsequent embryonic development after in vitro fertilization (IVF) and parthenogenetic activation (PA). After 40 h of IVM, intracellular GSH ...